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AAAI
2010
15 years 4 months ago
A Two-Dimensional Topic-Aspect Model for Discovering Multi-Faceted Topics
This paper presents the Topic-Aspect Model (TAM), a Bayesian mixture model which jointly discovers topics and aspects. We broadly define an aspect of a document as a characteristi...
Michael Paul, Roxana Girju
ALMOB
2008
124views more  ALMOB 2008»
15 years 3 months ago
A scoring matrix approach to detecting miRNA target sites
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Simon Moxon, Vincent Moulton, Jan T. Kim
BIOINFORMATICS
2008
106views more  BIOINFORMATICS 2008»
15 years 3 months ago
Small RNA gene identification and mRNA target predictions in bacteria
Motivation: Bacterial small ribonucleic acids (sRNAs) that are not ribosomal and transfer or messenger RNAs were initially identified in the sixties whereas their molecular functi...
Christophe Pichon, Brice Felden
132
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BMCBI
2008
122views more  BMCBI 2008»
15 years 3 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood
BMCBI
2008
133views more  BMCBI 2008»
15 years 3 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
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