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» Logic-Based Modeling in Systems Biology
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BMCBI
2006
156views more  BMCBI 2006»
14 years 12 months ago
Bayesian models for pooling microarray studies with multiple sources of replications
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
Erin M. Conlon, Joon J. Song, Jun S. Liu
BMCBI
2011
14 years 6 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
BMCBI
2007
143views more  BMCBI 2007»
14 years 12 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2008
106views more  BMCBI 2008»
14 years 12 months ago
Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology
Background: Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity an...
Mikel Egaña Aranguren, Erick Antezana, Mart...
AI
2008
Springer
14 years 12 months ago
The well-designed young mathematician
This paper complements McCarthy's "The well designed child", in part by putting it in a broader context, the space of possible well designed progeny, and in part by...
Aaron Sloman