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» MODBASE, a database of annotated comparative protein structu...
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JIB
2006
106views more  JIB 2006»
14 years 9 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
BMCBI
2008
123views more  BMCBI 2008»
14 years 10 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
BMCBI
2005
123views more  BMCBI 2005»
14 years 9 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2007
181views more  BMCBI 2007»
14 years 10 months ago
Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
Aleksey A. Porollo, Jaroslaw Meller
NAR
2006
74views more  NAR 2006»
14 years 9 months ago
NOPdb: Nucleolar Proteome Database
The Nucleolar Proteome Database (NOPdb) archives data on .700 proteins that were identified by multiple mass spectrometry (MS) analyses from highly purified preparations of human ...
Anthony Kar Lun Leung, Laura Trinkle-Mulcahy, Yun ...