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BMCBI
2010
138views more  BMCBI 2010»
13 years 6 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
BMCBI
2010
156views more  BMCBI 2010»
13 years 6 months ago
Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape
Background: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In gen...
Kristof Theys, Koen Deforche, Gertjan Beheydt, Yve...
BMCBI
2008
158views more  BMCBI 2008»
13 years 6 months ago
Bioinformatics in Italy: BITS2007, the fourth annual meeting of the Italian Society of Bioinformatics
spectives. A total of 149 abstracts were accepted and presented in the poster session and 31 of them were selected for oral presentation. At the opening of the meeting, Roderic Gui...
Graziano Pesole, Manuela Helmer-Citterich
CORR
2006
Springer
141views Education» more  CORR 2006»
13 years 6 months ago
Ideas by Statistical Mechanics (ISM)
Ideas by Statistical Mechanics (ISM) is a generic program to model evolution and propagation of ideas/patterns throughout populations subjected to endogenous and exogenous interac...
Lester Ingber
LOBJET
2006
196views more  LOBJET 2006»
13 years 6 months ago
Mapping High-Level Business Rules To and Through Aspects
Many object-oriented software applications contain implicit business rules. Although there exist many approaches that advocate the separation of rules, the rules' connections ...
María Agustina Cibrán, Maja D'Hondt,...