The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
Amrita Mathuriya, David A. Bader, Christine E. Hei...
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
Kenny Daily, Paul Rigor, Scott Christley, Xiaohui ...
Modern multicore processors, such as the Cell Broadband Engine, achieve high performance by equipping accelerator cores with small “scratchpad” memories. The price for increase...
Alastair F. Donaldson, Daniel Kroening, Philipp R&...
As evidenced by the popularity of MPI (Message Passing Interface), message passing is an effective programming technique for managing coarse-grained concurrency on distributed com...
Customizable meta-objects are a powerful abstraction for extending language features and implementation mechanisms, but interpretive execution suffers from severe performance penal...