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BMCBI
2010
88views more  BMCBI 2010»
14 years 10 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BMCBI
2008
83views more  BMCBI 2008»
14 years 10 months ago
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells
Background: Microarray technology has unveiled transcriptomic differences among tumors of various phenotypes, and, especially, brought great progress in molecular understanding of...
Atsushi Niida, Andrew D. Smith, Seiya Imoto, Shuic...
COMPLEXITY
2006
91views more  COMPLEXITY 2006»
14 years 9 months ago
The evolution of technology within a simple computer model
Technology--the collection of devices and methods available to human society--evolves by constructing new devices and methods from ones that previously exist, and in turn offering...
W. Brian Arthur, Wolfgang Polak
BMCBI
2007
101views more  BMCBI 2007»
14 years 9 months ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
IVC
2008
101views more  IVC 2008»
14 years 9 months ago
A system for processing handwritten bank checks automatically
In the US and many other countries, bank checks are preprinted with the account number and the check number in MICR ink and format; as such, these two numeric fields can be easily...
Rafael Palacios, Amar Gupta