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» Mapping Polymorphism
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SP
2008
IEEE
122views Security Privacy» more  SP 2008»
14 years 9 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...
TCBB
2008
115views more  TCBB 2008»
14 years 9 months ago
Highly Scalable Genotype Phasing by Entropy Minimization
A Single Nucleotide Polymorphism (SNP) is a position in the genome at which two or more of the possible four nucleotides occur in a large percentage of the population. SNPs accoun...
Alexander Gusev, Ion I. Mandoiu, Bogdan Pasaniuc
BMCBI
2005
163views more  BMCBI 2005»
14 years 9 months ago
CoaSim: A flexible environment for simulating genetic data under coalescent models
Background: Coalescent simulations are playing a large role in interpreting large scale intraspecific sequence or polymorphism surveys and for planning and evaluating association ...
Thomas Mailund, Mikkel H. Schierup, Christian N. S...
104
Voted
BMCBI
2011
14 years 1 months ago
ENGINES: exploring single nucleotide variation in entire human genomes
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
Jorge Amigo, Antonio Salas, Christopher Phillips
POPL
1998
ACM
15 years 1 months ago
From System F to Typed Assembly Language
abstractions, such as closures, tuples, and user-defined abstract data types. The type system ensures that well-typed programs cannot violate these abstractions. In addition, the ...
J. Gregory Morrisett, David Walker, Karl Crary, Ne...