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93
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BMCBI
2007
86views more  BMCBI 2007»
15 years 1 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
123
Voted
BMCBI
2004
206views more  BMCBI 2004»
15 years 1 months ago
Combining gene expression data from different generations of oligonucleotide arrays
Background: One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public re...
Kyu Baek Hwang, Sek Won Kong, Steven A. Greenberg,...
147
Voted
BMCBI
2007
174views more  BMCBI 2007»
15 years 1 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
127
Voted
BMCBI
2008
126views more  BMCBI 2008»
15 years 1 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
132
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BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
15 years 7 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li