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AI
2008
Springer
15 years 25 days ago
Solving quantified constraint satisfaction problems
We make a number of contributions to the study of the Quantified Constraint Satisfaction Problem (QCSP). The QCSP is an extension of the constraint satisfaction problem that can b...
Ian P. Gent, Peter Nightingale, Andrew G. D. Rowle...
126
Voted
BMCBI
2010
118views more  BMCBI 2010»
15 years 25 days ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha
99
Voted
BMCBI
2008
144views more  BMCBI 2008»
15 years 24 days ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
106
Voted
BMCBI
2007
123views more  BMCBI 2007»
15 years 24 days ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
CERA
2010
105views more  CERA 2010»
15 years 24 days ago
Implications of Alternative Multilevel Design Methods for Design Process Management
Multilevel design problems are typically decomposed into a hierarchy of distributed and strongly coupled sub-problems, each solved by design teams with specialized knowledge and t...
David Shahan, Carolyn Seepersad Seepersad