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» Markov constraints: steerable generation of Markov sequences
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ISMB
1998
15 years 1 months ago
A Hidden Markov Model for Predicting Transmembrane Helices in Protein Sequences
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
109
Voted
BMCBI
2006
92views more  BMCBI 2006»
15 years 12 days ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
DAGM
2006
Springer
15 years 4 months ago
Probabilistic De Novo Peptide Sequencing with Doubly Charged Ions
Sequencing of peptides by tandem mass spectrometry has matured to the key technology for proteomics. Noise in the measurement process strongly favors statistical models like NovoHM...
Hansruedi Peter, Bernd Fischer, Joachim M. Buhmann
BMCBI
2007
130views more  BMCBI 2007»
15 years 14 days ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
VTS
2000
IEEE
113views Hardware» more  VTS 2000»
15 years 4 months ago
Hidden Markov and Independence Models with Patterns for Sequential BIST
We propose a novel BIST technique for non-scan sequential circuits which does not modify the circuit under test. It uses a learning algorithm to build a hardware test sequence gen...
Laurent Bréhélin, Olivier Gascuel, G...