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CDC
2008
IEEE
15 years 6 months ago
Optimal control for combination therapy in cancer
Abstract— A mathematical model for the scheduling of angiogenic inhibitors in combination with a killing agent is considered as an optimal control problem. Initial results on the...
Urszula Ledzewicz, Heinz Schättler, Alberto d...
CORR
2007
Springer
110views Education» more  CORR 2007»
15 years 9 days ago
Computer algebra in systems biology
Systems biology focuses on the study of entire biological systems rather than on their individual components. With the emergence of high-throughput data generation technologies for...
Reinhard C. Laubenbacher, Bernd Sturmfels
TOCL
2012
235views Formal Methods» more  TOCL 2012»
13 years 2 months ago
Topological and Simplicial Models of Identity Types
racting these leads us to introduce the notion of a path object category. This is a relatively simple axiomatic framework, which is nonetheless sufficiently strong to allow the con...
Benno van den Berg, Richard Garner
DALT
2007
Springer
15 years 6 months ago
Integrating Agent Models and Dynamical Systems
Agent-based modelling approaches are usually based on logical languages, whereas in many areas dynamical system models based on differential equations are used. This paper shows ho...
Tibor Bosse, Alexei Sharpanskykh, Jan Treur
BMCBI
2010
126views more  BMCBI 2010»
14 years 9 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...