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BMCBI
2008
242views more  BMCBI 2008»
14 years 10 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
BMCBI
2008
132views more  BMCBI 2008»
14 years 10 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2008
104views more  BMCBI 2008»
14 years 10 months ago
Comparison of methods for estimating the nucleotide substitution matrix
Background: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different math...
Maribeth Oscamou, Daniel McDonald, Von Bing Yap, G...
BMCBI
2008
163views more  BMCBI 2008»
14 years 10 months ago
Nuclear staining and relative distance for quantifying epidermal differentiation in biomarker expression profiling
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
Thora Pommerencke, Thorsten Steinberg, Hartmut Dic...
CACM
2010
179views more  CACM 2010»
14 years 10 months ago
x86-TSO: a rigorous and usable programmer's model for x86 multiprocessors
Exploiting the multiprocessors that have recently become ubiquitous requires high-performance and reliable concurrent systems code, for concurrent data structures, operating syste...
Peter Sewell, Susmit Sarkar, Scott Owens, Francesc...
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