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BMCBI
2006
145views more  BMCBI 2006»
14 years 11 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
BMCBI
2006
85views more  BMCBI 2006»
14 years 11 months ago
Quality control for terms and definitions in ontologies and taxonomies
Background: Ontologies and taxonomies are among the most important computational resources for molecular biology and bioinformatics. A series of recent papers has shown that the G...
Jacob Köhler, Katherine Munn, Alexander R&uum...
CONSTRAINTS
2008
95views more  CONSTRAINTS 2008»
14 years 11 months ago
Efficient Sequence Alignment with Side-Constraints by Cluster Tree Elimination
Aligning DNA and protein sequences is a core technique in molecular biology. Often, it is desirable to include partial prior knowledge and conditions in an alignment. Going beyond...
Sebastian Will, Anke Busch, Rolf Backofen
ECEASST
2006
305views more  ECEASST 2006»
14 years 11 months ago
The ParMol Package for Frequent Subgraph Mining
Mining for frequent subgraphs in a graph database has become a popular topic in the last years. Algorithms to solve this problem are used in chemoinformatics to find common molecul...
Thorsten Meinl, Marc Wörlein, Olga Urzova, In...
IJSI
2008
122views more  IJSI 2008»
14 years 11 months ago
Mining Gene Expression Data using Domain Knowledge
Biology is now an information-intensive science and various research areas, like molecular biology, evolutionary biology or environmental biology, heavily depend on the availabilit...
Nicolas Pasquier, Claude Pasquier, Laurent Brisson...