Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
Shuxing Zhang, Kamal Kumar, Xiaohui Jiang, Anders ...
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Insight to complex problems may be revealed when domain data sets are viewed or structured in new and innovative ways. Systems approaches to biomedical problems fundamentally invo...
Donald J. Johann, Michael D. McGuigan, Stanimire T...
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...