Inference of phylogenetic trees using the maximum likelihood (ML) method is NP-hard. Furthermore, the computation of the likelihood function for huge trees of more than 1,000 orga...
Phylogenetic analysis is an area of computational biology concerned with the reconstruction of evolutionary relationships between organisms, genes, and gene families. Maximum likel...
Thomas M. Keane, Andrew J. Page, Thomas J. Naughto...
Phylogenetics has gained in public favor for the analysis of DNA sequence data as molecular biology has advanced. Among a number of algorithms for phylogenetics, the fastDNAml is c...
Phylogenetic trees are commonly reconstructed based on hard optimization problems such as maximum parsimony (MP) and maximum likelihood (ML). Conventional MP heuristics for produc...
Usman Roshan, Bernard M. E. Moret, Tandy Warnow, T...
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...