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ASC
2011
14 years 4 months ago
Autonomic fault-handling and refurbishment using throughput-driven assessment
A new paradigm for online EH regeneration using Genetic Algorithms (GAs) called Competitive Runtime Reconfiguration (CRR) is developed where performance is assessed based upon a b...
Ronald F. DeMara, Kening Zhang, Carthik A. Sharma
BMCBI
2011
14 years 4 months ago
CODA (CrossOver Distribution Analyzer): quantitative characterization of crossover position patterns along chromosomes
Background: During meiosis, homologous chromosomes exchange segments via the formation of crossovers. This phenomenon is highly regulated; in particular, crossovers are distribute...
Franck Gauthier, Olivier C. Martin, Matthieu Falqu...
BMCBI
2011
14 years 4 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
BMCBI
2011
14 years 4 months ago
Estimating developmental states of tumors and normal tissues using a linear time-ordered model
Background: Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic developme...
Bo Zhang, Beibei Chen, Tao Wu, Zhenyu Xuan, Xiaope...
BMCBI
2011
14 years 4 months ago
A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data
Background: Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze reactions to pro...
W. Andrew Lancaster, Jeremy L. Praissman, Farris L...
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