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BMCBI
2010
124views more  BMCBI 2010»
14 years 10 months ago
Estimating time since infection in early homogeneous HIV-1 samples using a poisson model
Background: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homo...
Elena E. Giorgi, Bob Funkhouser, Gayathri Athreya,...
BMCBI
2008
105views more  BMCBI 2008»
14 years 10 months ago
A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
Mano Sivaganesan, Shawn Seifring, Manju Varma, Ric...
BMCBI
2008
115views more  BMCBI 2008»
14 years 10 months ago
Improving peptide-MHC class I binding prediction for unbalanced datasets
Background: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such bin...
Ana Paula Sales, Georgia D. Tomaras, Thomas B. Kep...
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CANDC
2008
ACM
14 years 10 months ago
'Genome order index' should not be used for defining compositional constraints in nucleotide sequences
Background: The Z-curve is a three dimensional representation of DNA sequences proposed over a decade ago and has been extensively applied to sequence segmentation, horizontal gen...
Eran Elhaik, Dan Graur, Kresimir Josic
CORR
2010
Springer
156views Education» more  CORR 2010»
14 years 10 months ago
On the bias of BFS
Abstract--Breadth First Search (BFS) and other graph traversal techniques are widely used for measuring large unknown graphs, such as online social networks. It has been empiricall...
Maciej Kurant, Athina Markopoulou, Patrick Thiran
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