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BMCBI
2010
91views more  BMCBI 2010»
15 years 2 months ago
Algorithm-driven Artifacts in median polish summarization of Microarray data
Background: High-throughput measurement of transcript intensities using Affymetrix type oligonucleotide microarrays has produced a massive quantity of data during the last decade....
Federico M. Giorgi, Anthony M. Bolger, Marc Lohse,...
BMCBI
2008
145views more  BMCBI 2008»
15 years 2 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2007
125views more  BMCBI 2007»
15 years 2 months ago
Bayesian meta-analysis models for microarray data: a comparative study
Background: With the growing abundance of microarray data, statistical methods are increasingly needed to integrate results across studies. Two common approaches for meta-analysis...
Erin M. Conlon, Joon J. Song, Anna Liu
BMCBI
2007
144views more  BMCBI 2007»
15 years 1 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
BMCBI
2004
150views more  BMCBI 2004»
15 years 1 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...