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139
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BMCBI
2010
15 years 3 months ago
2010
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
145
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BMCBI
2008
15 years 3 months ago
2008
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
146
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BMCBI
2008
15 years 3 months ago
2008
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
127
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BMCBI
2008
15 years 3 months ago
2008
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
110
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BMCBI
2010
15 years 3 months ago
2010
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...