Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
This paper explores a new approach to community building. It is based on the concept of salutogenesis; a proactive approach to community health which seeks preventative measures i...
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
Gold standard mappings created by experts are at the core of alignment evaluation. At the same time, the process of manual evaluation is rarely discussed. While the practice of ha...
Anna Tordai, Jacco van Ossenbruggen, Guus Schreibe...