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» Measuring Model Transformation in Model Driven Development
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149
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BMCBI
2007
157views more  BMCBI 2007»
15 years 3 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
135
Voted
BMCBI
2008
115views more  BMCBI 2008»
15 years 3 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan
129
Voted
BMCBI
2008
188views more  BMCBI 2008»
15 years 3 months ago
anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data
Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification...
Nicola Zamboni, Anne Kümmel, Matthias Heinema...
147
Voted
BMCBI
2006
127views more  BMCBI 2006»
15 years 3 months ago
On the attenuation and amplification of molecular noise in genetic regulatory networks
Background: Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanis...
Bor-Sen Chen, Yu-Chao Wang
COMPGEOM
2006
ACM
15 years 9 months ago
Envelope surfaces
We construct a class of envelope surfaces in Rd , more precisely envelopes of balls. An envelope surface is a closed C1 (tangent continuous) manifold wrapping tightly around the u...
Nico Kruithof, Gert Vegter