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» Measuring software evolution
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158
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BMCBI
2010
176views more  BMCBI 2010»
15 years 3 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
139
Voted
BMCBI
2010
131views more  BMCBI 2010»
15 years 3 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
141
Voted
BMCBI
2008
128views more  BMCBI 2008»
15 years 3 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
150
Voted
BMCBI
2010
135views more  BMCBI 2010»
15 years 3 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
135
Voted
BMCBI
2007
137views more  BMCBI 2007»
15 years 3 months ago
Bayesian refinement of protein functional site matching
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
Kanti V. Mardia, Vysaul B. Nyirongo, Peter J. Gree...