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BMCBI
2008
118views more  BMCBI 2008»
15 years 6 months ago
Evaluation of phylogenetic footprint discovery for predicting bacterial cis-regulatory elements and revealing their evolution
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
Rekin's Janky, Jacques van Helden
BMCBI
2008
142views more  BMCBI 2008»
15 years 6 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
BMCBI
2008
103views more  BMCBI 2008»
15 years 6 months ago
The VirusBanker database uses a Java program to allow flexible searching through Bunyaviridae sequences
Background: Viruses of the Bunyaviridae have segmented negative-stranded RNA genomes and several of them cause significant disease. Many partial sequences have been obtained from ...
Mathieu Fourment, Mark J. Gibbs
BMCBI
2006
111views more  BMCBI 2006»
15 years 6 months ago
PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Tomer Hertz, Chen Yanover
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
MicroTar: predicting microRNA targets from RNA duplexes
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Rahul Thadani, Martti T. Tammi