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BMCBI
2005
87views more  BMCBI 2005»
15 years 1 months ago
ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related protei
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Tomas Ohlson, Arne Elofsson
BMCBI
2010
109views more  BMCBI 2010»
15 years 2 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
OOPSLA
2010
Springer
15 years 8 days ago
An input-centric paradigm for program dynamic optimizations
Accurately predicting program behaviors (e.g., locality, dependency, method calling frequency) is fundamental for program optimizations and runtime adaptations. Despite decades of...
Kai Tian, Yunlian Jiang, Eddy Z. Zhang, Xipeng She...
DISCEX
2003
IEEE
15 years 7 months ago
Achieving Principled Assuredly Trustworthy Composable Systems and Networks
Huge challenges exist with systems and networks that must dependably satisfy stringent requirements for security, reliability, and other attributes of trustworthiness. Drawing on ...
Peter G. Neumann
115
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CICLING
2008
Springer
15 years 3 months ago
Semantic and Syntactic Features for Dutch Coreference Resolution
We investigate the effect of encoding additional semantic and syntactic information sources in a classification-based machine learning approach to the task of coreference resolutio...
Iris Hendrickx, Véronique Hoste, Walter Dae...