Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
Recently developed gene set analysis methods evaluate differential expression patterns of gene groups instead of those of individual genes. This approach especially targets gene g...
Abstract. We demonstrate a set-level approach to the integration of multiple platform gene expression data for predictive classification and show its utility for boosting classi...
DNA microarray technology provides a broad snapshot of the state of the cell by measuring the expression levels of thousands of genes simultaneously. Visualization techniques can ...
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...