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CSB
2005
IEEE
133views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Biological Pathway Prediction from Multiple Data Sources Using Iterative Bayesian Updating
There is a diversity of functional genomics data, such as gene expression data from microarray experiments, phenotypic data from gene deletion experiments, protein-protein interac...
Corey Powell, Joshua M. Stuart
BMCBI
2008
155views more  BMCBI 2008»
14 years 9 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
KDD
2008
ACM
206views Data Mining» more  KDD 2008»
15 years 10 months ago
Identifying biologically relevant genes via multiple heterogeneous data sources
Selection of genes that are differentially expressed and critical to a particular biological process has been a major challenge in post-array analysis. Recent development in bioin...
Zheng Zhao, Jiangxin Wang, Huan Liu, Jieping Ye, Y...
BMCBI
2007
152views more  BMCBI 2007»
14 years 9 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim
RECOMB
2002
Springer
15 years 10 months ago
From promoter sequence to expression: a probabilistic framework
We present a probabilistic framework that models the process by which transcriptional binding explains the mRNA expression of different genes. Our joint probabilistic model unifie...
Eran Segal, Yoseph Barash, Itamar Simon, Nir Fried...