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BMCBI
2008
105views more  BMCBI 2008»
14 years 9 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
BMCBI
2010
126views more  BMCBI 2010»
14 years 9 months ago
GeneBrowser 2: an application to explore and identify common biological traits in a set of genes
Background: The development of high-throughput laboratory techniques created a demand for computer-assisted result analysis tools. Many of these techniques return lists of genes w...
Joel Arrais, João Fernandes, João Pe...
BMCBI
2007
166views more  BMCBI 2007»
14 years 9 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour
WABI
2009
Springer
124views Bioinformatics» more  WABI 2009»
15 years 4 months ago
Mimosa: Mixture Model of Co-expression to Detect Modulators of Regulatory Interaction
Background: Functionally related genes tend to be correlated in their expression patterns across multiple conditions and/or tissue-types. Thus co-expression networks are often use...
Matthew Hansen, Logan Everett, Larry Singh, Sridha...
JCP
2006
157views more  JCP 2006»
14 years 9 months ago
CF-GeNe: Fuzzy Framework for Robust Gene Regulatory Network Inference
Most Gene Regulatory Network (GRN) studies ignore the impact of the noisy nature of gene expression data despite its significant influence upon inferred results. This paper present...
Muhammad Shoaib B. Sehgal, Iqbal Gondal, Laurence ...