It is well-known that for high dimensional data clustering, standard algorithms such as EM and the K-means are often trapped in local minimum. Many initialization methods were pro...
Chris H. Q. Ding, Xiaofeng He, Hongyuan Zha, Horst...
Background: The Golden Spike data set has been used to validate a number of methods for summarizing Affymetrix data sets, sometimes with seemingly contradictory results. Much less...
Differential protein expression analysis is one of the main challenges in proteomics. It denotes the search for proteins, whose encoding genes are differentially expressed under a...
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
Recent work has demonstrated that microRNAs (miRNAs) are involved in critical biological processes by suppressing the translation of coding genes. This work develops an integrated...
Paul Wei-Che Hsu, Hsien-Da Huang, Sheng-Da Hsu, Li...