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BMCBI
2006
107views more  BMCBI 2006»
14 years 9 months ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...
BMCBI
2008
166views more  BMCBI 2008»
14 years 9 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
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EDBTW
2006
Springer
15 years 1 months ago
An Integrated Platform for Analyzing Molecular-Biological Data Within Clinical Studies
To investigate molecular-biological causes and effects of diseases and their therapies it becomes increasingly important to combine data from clinical trials with high volumes of e...
Toralf Kirsten, Jörg Lange, Erhard Rahm
ECAI
2004
Springer
15 years 1 months ago
Avoiding Data Overfitting in Scientific Discovery: Experiments in Functional Genomics
Functional genomics is a typical scientific discovery domain characterized by a very large number of attributes (genes) relative to the number of examples (observations). The dang...
Dragan Gamberger, Nada Lavrac
BMCBI
2007
105views more  BMCBI 2007»
14 years 9 months ago
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor sti
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...