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» Metabolic networks analysis using convex optimization
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BMCBI
2010
133views more  BMCBI 2010»
13 years 6 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
IV
2008
IEEE
296views Visualization» more  IV 2008»
14 years 20 days ago
Revealing Subnetwork Roles using Contextual Visualization: Comparison of Metabolic Networks
This article is addressing a recurrent problem in biology: mining newly built large scale networks. Our approach consists in comparing these new networks to well known ones. The v...
Romain Bourqui, Fabien Jourdan
BMCBI
2006
104views more  BMCBI 2006»
13 years 6 months ago
MANET: tracing evolution of protein architecture in metabolic networks
Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
GG
2004
Springer
13 years 11 months ago
Analysis of Metabolic Pathways by Graph Transformation
Biochemical pathways, such as metabolic, regulatory, and signal transduction pathways, constitute complex networks of functional and physical interactions between molecular species...
Francesc Rosselló, Gabriel Valiente
BMCBI
2010
191views more  BMCBI 2010»
13 years 6 months ago
BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...