39 search results - page 6 / 8 » Metabolic pathways variability and sequence networks compari... |
NAR
2008
14 years 10 months ago
2008
The molecular basis of drug action is often not well understood. This is partly because the very abundant and diverse information generated in the past decades on drugs is hidden ...
BMCBI
2010
14 years 10 months ago
2010
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
103
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BMCBI
2006
14 years 10 months ago
2006
Background: Recent advances with high-throughput methods in life-science research have increased the need for automatized data analysis and visual exploration techniques. Sophisti...
106
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ECCB
2005
IEEE
15 years 3 months ago
2005
IEEE
Many areas of modern biology are concerned with the management, storage, visualization, comparison, and analysis of networks. For instance, networks are used to model signal trans...
BMCBI
2008
14 years 10 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...