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128
Voted
BMCBI
2010
15 years 28 days ago
2010
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
97
Voted
BMCBI
2007
15 years 28 days ago
2007
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
BMCBI
2006
15 years 26 days ago
2006
Background: There is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are ...
109
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BMCBI
2007
15 years 24 days ago
2007
Background: The web has seen an explosion of chemistry and biology related resources in the last 15 years: thousands of scientific journals, databases, wikis, blogs and resources ...
129
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JIB
2006
15 years 23 days ago
2006
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...