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BMCBI
2006
145views more  BMCBI 2006»
15 years 18 days ago
Fast-Find: A novel computational approach to analyzing combinatorial motifs
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
98
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BMCBI
2006
109views more  BMCBI 2006»
15 years 18 days ago
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions
Background: Phytochromes are photoreceptors, discovered in plants, that control a wide variety of developmental processes. They have also been found in bacteria and fungi, but for...
Tilman Lamparter
BMCBI
2006
114views more  BMCBI 2006»
15 years 18 days ago
Taxonomic colouring of phylogenetic trees of protein sequences
Background: Phylogenetic analyses of protein families are used to define the evolutionary relationships between homologous proteins. The interpretation of protein-sequence phyloge...
Gareth Palidwor, Emmanuel G. Reynaud, Miguel A. An...
91
Voted
BMCBI
2006
140views more  BMCBI 2006»
15 years 18 days ago
SNP-PHAGE - High throughput SNP discovery pipeline
Background: Single nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
120
Voted
BMCBI
2006
125views more  BMCBI 2006»
15 years 18 days ago
Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow
Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they...
Hiraku Morisawa, Mikako Hirota, Tosifusa Toda