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BMCBI
2008
117views more  BMCBI 2008»
14 years 9 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
BMCBI
2008
125views more  BMCBI 2008»
14 years 9 months ago
Disambiguation of biomedical text using diverse sources of information
Background: Like text in other domains, biomedical documents contain a range of terms with more than one possible meaning. These ambiguities form a significant obstacle to the aut...
Mark Stevenson, Yikun Guo, Robert J. Gaizauskas, D...
81
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BMCBI
2004
153views more  BMCBI 2004»
14 years 9 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
JMLR
2010
134views more  JMLR 2010»
14 years 4 months ago
Bayesian Algorithms for Causal Data Mining
We present two Bayesian algorithms CD-B and CD-H for discovering unconfounded cause and effect relationships from observational data without assuming causal sufficiency which prec...
Subramani Mani, Constantin F. Aliferis, Alexander ...
BMCBI
2010
135views more  BMCBI 2010»
14 years 9 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...