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94
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BMCBI
2010
125views more  BMCBI 2010»
15 years 29 days ago
A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins
Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of...
Mats Ensterö, Örjan Åkerborg, Dani...
99
Voted
BMCBI
2010
135views more  BMCBI 2010»
15 years 29 days ago
HDAPD: a web tool for searching the disease-associated protein structures
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Yi-Ruen Lin, Hsin-Yuan Wei, Tsung-Lin Tsai, Thy-Ho...
107
Voted
BMCBI
2010
150views more  BMCBI 2010»
15 years 29 days ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
105
Voted
BMCBI
2010
172views more  BMCBI 2010»
15 years 29 days ago
Accessing the SEED genome databases via Web services API: tools for programmers
Background: The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems ...
Terry Disz, Sajia Akhter, Daniel Cuevas, Robert Ol...
BMCBI
2010
139views more  BMCBI 2010»
15 years 29 days ago
RNAstructure: software for RNA secondary structure prediction and analysis
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...
Jessica S. Reuter, David H. Mathews
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