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105
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BMCBI
2008
153views more  BMCBI 2008»
15 years 28 days ago
AWclust: point-and-click software for non-parametric population structure analysis
Background: Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STRUCTURE and L-POP, usually ass...
Xiaoyi Gao, Joshua D. Starmer
96
Voted
BMCBI
2010
146views more  BMCBI 2010»
15 years 28 days ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
89
Voted
BMCBI
2010
134views more  BMCBI 2010»
15 years 28 days ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
91
Voted
BMCBI
2008
92views more  BMCBI 2008»
15 years 28 days ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
115
Voted
BMCBI
2007
182views more  BMCBI 2007»
15 years 28 days ago
Additive risk survival model with microarray data
Background: Microarray techniques survey gene expressions on a global scale. Extensive biomedical studies have been designed to discover subsets of genes that are associated with ...
Shuangge Ma, Jian Huang
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