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» Microarray Gene Expression Data Analysis
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BMCBI
2004
142views more  BMCBI 2004»
15 years 2 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...
112
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IDA
2003
Springer
15 years 7 months ago
Obtaining Quality Microarray Data via Image Reconstruction
Abstract. This paper introduces a novel method for processing spotted microarray images, inspired from image reconstruction. Instead of the usual approach that focuses on the signa...
Paul O'Neill, George D. Magoulas, Xiaohui Liu
97
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BMCBI
2006
88views more  BMCBI 2006»
15 years 2 months ago
A two-sample Bayesian t-test for microarray data
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Richard J. Fox, Matthew W. Dimmic
BMCBI
2005
141views more  BMCBI 2005»
15 years 2 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
BMCBI
2008
146views more  BMCBI 2008»
15 years 2 months ago
Rank-based edge reconstruction for scale-free genetic regulatory networks
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai