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BIBE
2007
IEEE
155views Bioinformatics» more  BIBE 2007»
15 years 8 months ago
Partial Mixture Model for Tight Clustering in Exploratory Gene Expression Analysis
Abstract—In this paper we demonstrate the inherent robustness of minimum distance estimator that makes it a potentially powerful tool for parameter estimation in gene expression ...
Yinyin Yuan, Chang-Tsun Li
BMCBI
2007
168views more  BMCBI 2007»
15 years 2 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
135
Voted
BMCBI
2006
123views more  BMCBI 2006»
15 years 2 months ago
Permutation test for periodicity in short time series data
Background: Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretica...
Andrey A. Ptitsyn, Sanjin Zvonic, Jeffrey M. Gimbl...
108
Voted
BMCBI
2007
114views more  BMCBI 2007»
15 years 2 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
110
Voted
BMCBI
2006
118views more  BMCBI 2006»
15 years 2 months ago
Microarray image analysis: background estimation using quantile and morphological filters
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
Anders Bengtsson, Henrik Bengtsson