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BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
The Virtual Insect Brain protocol: creating and comparing standardized neuroanatomy
Background: In the fly Drosophila melanogaster, new genetic, physiological, molecular and behavioral techniques for the functional analysis of the brain are rapidly accumulating. ...
Arnim Jenett, Johannes E. Schindelin, Martin Heise...
JMLR
2010
163views more  JMLR 2010»
14 years 4 months ago
Dense Message Passing for Sparse Principal Component Analysis
We describe a novel inference algorithm for sparse Bayesian PCA with a zero-norm prior on the model parameters. Bayesian inference is very challenging in probabilistic models of t...
Kevin Sharp, Magnus Rattray
BMCBI
2010
130views more  BMCBI 2010»
14 years 9 months ago
A statistical approach to finding overlooked genetic associations
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
BMCBI
2007
114views more  BMCBI 2007»
14 years 9 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
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BMCBI
2008
95views more  BMCBI 2008»
14 years 9 months ago
Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
Joseph W. Foley, Fumiaki Katagiri