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BMCBI
2008
129views more  BMCBI 2008»
14 years 9 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2006
181views more  BMCBI 2006»
14 years 9 months ago
Automatic pathway building in biological association networks
Background: Scientific literature is a source of the most reliable and comprehensive knowledge about molecular interaction networks. Formalization of this knowledge is necessary f...
Anton Yuryev, Zufar Mulyukov, Ekaterina Kotelnikov...
BMCBI
2006
114views more  BMCBI 2006»
14 years 9 months ago
PROMPT: a protein mapping and comparison tool
Background: Comparison of large protein datasets has become a standard task in bioinformatics. Typically researchers wish to know whether one group of proteins is significantly en...
Thorsten Schmidt, Dmitrij Frishman
BMCBI
2002
137views more  BMCBI 2002»
14 years 9 months ago
ORFer - retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files
Background: Functional genomics involves the parallel experimentation with large sets of proteins. This requires management of large sets of open reading frames as a prerequisite ...
Konrad Büssow, Steve Hoffmann, Volker Sievert
ECCB
2005
IEEE
15 years 3 months ago
A query language for biological networks
Many areas of modern biology are concerned with the management, storage, visualization, comparison, and analysis of networks. For instance, networks are used to model signal trans...
Ulf Leser