Background: The underlying goal of microarray experiments is to identify gene expression patterns across different experimental conditions. Genes that are contained in a particula...
Johanna S. Hardin, Aya Mitani, Leanne Hicks, Brian...
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Background: Pre-processing methods for two-sample long oligonucleotide arrays, specifically the Agilent technology, have not been extensively studied. The goal of this study is to...
Marianna Zahurak, Giovanni Parmigiani, Wayne Yu, R...
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...