It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
Background: To identify differentially expressed genes across experimental conditions in oligonucleotide microarray experiments, existing statistical methods commonly use a summar...
Leah Barrera, Chris Benner, Yong-Chuan Tao, Elizab...
Background: Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data. Although gene sets are defined a ...
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...