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» Microarray Gene Expression Data Analysis
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BMCBI
2004
124views more  BMCBI 2004»
15 years 2 months ago
XHM: A system for detection of potential cross hybridizations in DNA microarrays
Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be...
Kristian Flikka, Fekadu Yadetie, Astrid Lægr...
BMCBI
2007
104views more  BMCBI 2007»
15 years 2 months ago
Comparative evaluation of gene-set analysis methods
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
Qi Liu, Irina Dinu, Adeniyi J. Adewale, John D. Po...
BMCBI
2010
125views more  BMCBI 2010»
14 years 9 months ago
ProbFAST: Probabilistic Functional Analysis System Tool
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
Israel T. da Silva, Ricardo Z. N. Vêncio, Th...
BMCBI
2010
156views more  BMCBI 2010»
15 years 2 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
SIAMCOMP
2008
123views more  SIAMCOMP 2008»
15 years 2 months ago
Approximation Algorithms for Biclustering Problems
One of the main goals in the analysis of microarray data is to identify groups of genes and groups of experimental conditions (including environments, individuals, and tissues) tha...
Lusheng Wang, Yu Lin, Xiaowen Liu