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» Mining Gene Expression Data using Domain Knowledge
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BMCBI
2010
214views more  BMCBI 2010»
15 years 2 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
154views more  BMCBI 2010»
15 years 2 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
119
Voted
BMCBI
2007
152views more  BMCBI 2007»
15 years 2 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim
148
Voted
BICOB
2009
Springer
14 years 11 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...
WILF
2005
Springer
112views Fuzzy Logic» more  WILF 2005»
15 years 7 months ago
NEC for Gene Expression Analysis
Aim of this work is to apply a novel comprehensive machine learning tool for data mining to preprocessing and interpretation of gene expression data. Furthermore, some visualizatio...
Roberto Amato, Angelo Ciaramella, N. Deniskina, Ca...