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» Mining Gene Expression Data using Domain Knowledge
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BMCBI
2010
214views more  BMCBI 2010»
14 years 12 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
154views more  BMCBI 2010»
14 years 12 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
BMCBI
2007
152views more  BMCBI 2007»
14 years 12 months ago
Difference-based clustering of short time-course microarray data with replicates
Background: There are some limitations associated with conventional clustering methods for short time-course gene expression data. The current algorithms require prior domain know...
Jihoon Kim, Ju Han Kim
BICOB
2009
Springer
14 years 9 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...
WILF
2005
Springer
112views Fuzzy Logic» more  WILF 2005»
15 years 5 months ago
NEC for Gene Expression Analysis
Aim of this work is to apply a novel comprehensive machine learning tool for data mining to preprocessing and interpretation of gene expression data. Furthermore, some visualizatio...
Roberto Amato, Angelo Ciaramella, N. Deniskina, Ca...