Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
Abstract. One of the exciting scientific challenges in functional genomics concerns the discovery of biologically relevant patterns from gene expression data. For instance, it is e...