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» Mining Protein Sequences for Motifs
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BMCBI
2005
190views more  BMCBI 2005»
14 years 9 months ago
Species-specific analysis of protein sequence motifs using mutual information
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
Jan Hummel, Nima Keshvari, Wolfram Weckwerth, Joac...
ALMOB
2007
74views more  ALMOB 2007»
14 years 9 months ago
Evaluating deterministic motif significance measures in protein databases
Background: Assessing the outcome of motif mining algorithms is an essential task, as the number of reported motifs can be very large. Significance measures play a central role in...
Pedro Gabriel Ferreira, Paulo J. Azevedo
BIBM
2008
IEEE
113views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Towards Site-Based Protein Functional Annotations
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
Seak Fei Lei, Jun Huan
NIPS
2004
14 years 11 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
CSR
2006
Springer
15 years 1 months ago
Fast Motif Search in Protein Sequence Databases
Regular expression pattern matching is widely used in computational biology. Searching through a database of sequences for a motif (a simple regular expression), or its variations...
Elena Zheleva, Abdullah N. Arslan