AREsite is an online resource for the detailed investigation of AU-rich elements (ARE) in vertebrate mRNA 30 -untranslated regions (UTRs). AREs are one of the most prominent cis-a...
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...