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» Mining Protein Sequences for Motifs
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79
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SDM
2008
SIAM
112views Data Mining» more  SDM 2008»
14 years 11 months ago
A pattern mining approach toward discovering generalized sequence signatures
Typically, sequence signatures, such as motifs and domains, are assumed to be localized in one region of a sequence or are derived as combinations of the former. We generalize the...
Dietmar H. Dorr, Anne Denton
DMKD
2003
ACM
110views Data Mining» more  DMKD 2003»
15 years 2 months ago
Weave amino acid sequences for protein secondary structure prediction
Given a known protein sequence, predicting its secondary structure can help understand its three-dimensional (tertiary) structure, i.e., the folding. In this paper, we present an ...
Xiaochun Yang, Bin Wang
75
Voted
ISMB
1996
14 years 11 months ago
The Megaprior Heuristic for Discovering Protein Sequence Patterns
Several computeralgorithms for discovering patterns in groups of protein sequences are in use that are basedon fitting the parametersof a statistical model to a group of related s...
Timothy L. Bailey, Michael Gribskov
95
Voted
BMCBI
2008
163views more  BMCBI 2008»
14 years 9 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
BMCBI
2006
108views more  BMCBI 2006»
14 years 9 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...