Typically, sequence signatures, such as motifs and domains, are assumed to be localized in one region of a sequence or are derived as combinations of the former. We generalize the...
Given a known protein sequence, predicting its secondary structure can help understand its three-dimensional (tertiary) structure, i.e., the folding. In this paper, we present an ...
Several computeralgorithms for discovering patterns in groups of protein sequences are in use that are basedon fitting the parametersof a statistical model to a group of related s...
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...