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» Mining Protein Sequences for Motifs
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BMCBI
2010
109views more  BMCBI 2010»
14 years 9 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...
CLUSTER
2007
IEEE
15 years 4 months ago
Sequential and parallel implementation of a constraint-based algorithm for searching protein structures
— Data mining in biological structure libraries can be a powerful tool to better understand biochemical processes. This article introduces the LISA algorithm which enables the re...
Sascha Hunold, Thomas Rauber, Georg Wille
BMCBI
2010
167views more  BMCBI 2010»
14 years 9 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
BMCBI
2007
167views more  BMCBI 2007»
14 years 9 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
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ICDE
2009
IEEE
173views Database» more  ICDE 2009»
14 years 7 months ago
Efficient Mining of Closed Repetitive Gapped Subsequences from a Sequence Database
There is a huge wealth of sequence data available, for example, customer purchase histories, program execution traces, DNA, and protein sequences. Analyzing this wealth of data to ...
Bolin Ding, David Lo, Jiawei Han, Siau-Cheng Khoo