Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
— Data mining in biological structure libraries can be a powerful tool to better understand biochemical processes. This article introduces the LISA algorithm which enables the re...
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
There is a huge wealth of sequence data available, for example, customer purchase histories, program execution traces, DNA, and protein sequences. Analyzing this wealth of data to ...