Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...
Similarity search in sequence databases is of paramount importance in bioinformatics research. As the size of the genomic databases increases, similarity search of proteins in the...
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...